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Talibegron HCl

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Talibegron HCl
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Cat #: V5383 CAS #: 178600-17-4 Purity ≥ 99%

Description: Talibegron HCl (ZD-2079; ICI-D-2079, SCH-417849), the hydrochloride Talibegron, is a novel and potent β3 adrenergic receptor agonist (pD2 = 3.72 on phenylephrine-preconstricted rat mesenteric artery) with potent vasorelaxant effects.

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Molecular Weight (MW)351.827  
Molecular FormulaC18H22ClNO4
CAS No.178600-17-4
SynonymsSCH417849
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.