Apicidin

This product is for research use only, not for human use. We do not sell to patients.

Apicidin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$985Check With Us
100mg$1450Check With Us
200mg$2172Check With Us

Cat #: V11458 CAS #: 183506-66-3 Purity ≥ 99%

Description: Apicidin (OSI-2040; OSI2040) is a novel and potent histone deacetylases (HDAC) inhibitor and apoptosis inducer with potential anticancer activity.

References: Han JW, et al. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Cancer Res. 2000 Nov 1;60(21):6068-74.

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Molecular Weight (MW)623.78
Molecular FormulaC34H49N5O6
CAS No.183506-66-3
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6031 mL8.0156 mL16.0313 mL32.0626 mL
5mM0.3206 mL1.6031 mL3.2063 mL6.4125 mL
10mM0.1603 mL0.8016 mL1.6031 mL3.2063 mL
20mM0.0802 mL0.4008 mL0.8016 mL1.6031 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.