FT895

This product is for research use only, not for human use. We do not sell to patients.

FT895
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$1150To Be Confirmed
100mg$1675To Be Confirmed
200mg$2512To Be Confirmed

Cat #: V31524 CAS #: 2225728-57-2 Purity ≥ 99%

Description: FT895 (FT-895; FT 895 ) is a novel and potent HDAC11 (histone deacetylase) inhibitor (IC50 = 3 nM).

References: Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1; 28(12):2143-2147.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)352.31
Molecular FormulaC16H15F3N4O2
CAS No.2225728-57-2
ProtocolIn VitroFT895 is a highly selective HDAC11 inhibitor that has shown more than 10-fold selectivity to 1000 other members of the HDAC family
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8384 mL14.1920 mL28.3841 mL56.7682 mL
5mM0.5677 mL2.8384 mL5.6768 mL11.3536 mL
10mM0.2838 mL1.4192 mL2.8384 mL5.6768 mL
20mM0.1419 mL0.7096 mL1.4192 mL2.8384 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.