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SCH900776 S-isomer (MK-8776 S-isomer)

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SCH900776 S-isomer (MK-8776 S-isomer)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750Check With Us
250mg$1350Check With Us
500mg$2025Check With Us
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Cat #: V28897 CAS #: 891494-64-7 Purity ≥ 99%

Description: SCH900776 S-isomer is the S-isomer of SCH900776 (MK-8776), which is a novel, highly potent and selective Chk1 (cell cycle checkpoint kinase 1) inhibitor with IC50 of 3 nM in a cell-free assay.

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Molecular Weight (MW)376.25
Molecular FormulaC15H18BrN7
CAS No.891494-64-7
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6578 mL13.2890 mL26.5781 mL53.1561 mL
5mM0.5316 mL2.6578 mL5.3156 mL10.6312 mL
10mM0.2658 mL1.3289 mL2.6578 mL5.3156 mL
20mM0.1329 mL0.6645 mL1.3289 mL2.6578 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.