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TAK-960 dihydrochloride

This product is for research use only, not for human use. We do not sell to patients.

TAK-960 dihydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1080Check With Us
500mg$1550Check With Us
1g$2325Check With Us

Cat #: V4582 CAS #: 1137868-52-0 Purity ≥ 98%

Description: TAK-960 DiHCl, the dihydrochloride salt of TAK960, is an orally bioavailable, potent, and selective PLK1 polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.8 nM at 10 μM ATP.

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Product Promise

Promise
Molecular Weight (MW)634.52
Molecular FormulaC₂₇H₃₆Cl₂F₃N₇O₃
CAS No.1137868-52-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5760 mL7.8800 mL15.7599 mL31.5199 mL
5mM0.3152 mL1.5760 mL3.1520 mL6.3040 mL
10mM0.1576 mL0.7880 mL1.5760 mL3.1520 mL
20mM0.0788 mL0.3940 mL0.7880 mL1.5760 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.