3MB-PP1

This product is for research use only, not for human use. We do not sell to patients.

3MB-PP1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1100Check With Us
250mg$1800Check With Us
500mg$2700Check With Us

Cat #: V60036 CAS #: 956025-83-5 Purity ≥ 99%

Description: 3MB-PP1, also known as 3-MB-PP1, 3 MB-PP1, is a Polo-like kinase 1 (PLK1) inhibitor.

References: Burkard ME, et al. Enabling and disabling polo-like kinase 1 inhibition through chemical genetics. ACS Chem Biol. 2012 Jun 15;7(6):978-81.

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Molecular Weight (MW)295.38
Molecular FormulaC17H21N5
CAS No.956025-83-5
ProtocolIn Vitro3MB-PP1 (5 μM; 3 hours) stimulates hyphal growth in a strain bearing analog-sensitive alleles of SSN3
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3855 mL16.9273 mL33.8547 mL67.7094 mL
5mM0.6771 mL3.3855 mL6.7709 mL13.5419 mL
10mM0.3385 mL1.6927 mL3.3855 mL6.7709 mL
20mM0.1693 mL0.8464 mL1.6927 mL3.3855 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.