Manidipine 2HCl

This product is for research use only, not for human use. We do not sell to patients.

Manidipine 2HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$249Check With Us
1g$450Check With Us
5g$1215Check With Us

Cat #: V1551 CAS #: 89226-75-5 Purity ≥ 98%

Description: Manidipine 2HCl (also called CV-4093; CV4093), the dihydrochloride salt form of Manidipine, is a calcium channel blocker/CCB that is used clinically as an antihypertensive agent.

References: Buset Ríos N, Rodríguez Esparragón F, Fernández-Andrade Rodríguez C, et al. Vascular and metabolic properties of manidipine . Nefrologia. 2011;31(3):268-74.

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Product Promise

Promise
Molecular Weight (MW)683.62
Molecular FormulaC35H38N4O6.2HCl
CAS No.89226-75-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 21 mg/mL (30.7 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Solubility In Vivo2% DMSO+30% PEG 300+ddH2O: 2 mg/mL
SynonymsCV-4093; CV4093; CV 4093
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4628 mL7.3140 mL14.6280 mL29.2560 mL
5mM0.2926 mL1.4628 mL2.9256 mL5.8512 mL
10mM0.1463 mL0.7314 mL1.4628 mL2.9256 mL
20mM0.0731 mL0.3657 mL0.7314 mL1.4628 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.