Oncrasin-1

This product is for research use only, not for human use. We do not sell to patients.

Oncrasin-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$980Check With Us
500mg$1420Check With Us
1g$2130Check With Us

Cat #: V4796 CAS #: 75629-57-1 Purity ≥ 98%

Description: Oncrasin-1 is a novel and potent antitumor agent that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; it also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells.

References: Guo W, et al. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008 Sep 15;68(18):7403-8.

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Product Promise

Promise
Molecular Weight (MW)269.73
Molecular FormulaC16H12ClNO
CAS No.75629-57-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.7074 mL18.5371 mL37.0741 mL74.1482 mL
5mM0.7415 mL3.7074 mL7.4148 mL14.8296 mL
10mM0.3707 mL1.8537 mL3.7074 mL7.4148 mL
20mM0.1854 mL0.9269 mL1.8537 mL3.7074 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.