ZINC00881524 (ROCK inhibitor)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $450 | Check With Us |
| 500mg | $700 | Check With Us |
| 1g | $1050 | Check With Us |
: Cat #: V2558 CAS #: 557782-81-7 Purity ≥ 98%
Description: ZINC00881524 is a novel, potent and selective ROCK inhibitor.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 380.46 |
|---|---|
| Molecular Formula | C21H20N2O3S |
| CAS No. | 557782-81-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 76 mg/mL (199.8 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 3 mg/mL (7.9 mM) | |
| Solubility In Vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O: 5mg/mL |
| Synonyms | ZINC00881524; ZINC-00881524; ZINC 00881524. Chemical Name: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide InChi Key: DQNMDJGZWFZNHS-UHFFFAOYSA-N InChi Code: InChI=1S/C21H20N2O3S/c1-25-16-9-7-13(11-17(16)26-2)12-19(24)22-21-23-20-15-6-4-3-5-14(15)8-10-18(20)27-21/h3-7,9,11H,8,10,12H2,1-2H3,(H,22,23,24) SMILES Code: O=C(NC1=NC2=C(CCC3=C2C=CC=C3)S1)CC4=CC=C(OC)C(OC)=C4 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6284 mL | 13.1420 mL | 26.2840 mL | 52.5679 mL |
| 5mM | 0.5257 mL | 2.6284 mL | 5.2568 mL | 10.5136 mL |
| 10mM | 0.2628 mL | 1.3142 mL | 2.6284 mL | 5.2568 mL |
| 20mM | 0.1314 mL | 0.6571 mL | 1.3142 mL | 2.6284 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.