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Maropitant (CJ11,972; CJ-11972)

This product is for research use only, not for human use. We do not sell to patients.

Maropitant (CJ11,972; CJ-11972)
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Size Price Stock
250mg$1350Check With Us
500mg$2050Check With Us
1g$3075Check With Us

Cat #: V15365 CAS #: 147116-67-4 Purity ≥ 98%

Description: Maropitan (CJ11972; CJ11972) is a novel, potent, selective and orally bioactive antagonist of neurokinin (NK1) receptor.

References: Hay Kraus BL. Efficacy of maropitant in preventing vomiting in dogs premedicated with hydromorphone. Vet Anaesth Analg. 2013 Jan;40(1):28-34.

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Product Promise

Promise
Molecular Weight (MW)468.67
Molecular FormulaC32H40N2O
CAS No.147116-67-4
ProtocolIn VivoTreatment with 1 mg/kg Maropitant citrate, significantly reduces the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreases MAC by 16%. In contrast, epidural administration of either saline or Maropitant does not change the MAC (2.17% and 1.92 %, respectively).
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1337 mL10.6685 mL21.3370 mL42.6739 mL
5mM0.4267 mL2.1337 mL4.2674 mL8.5348 mL
10mM0.2134 mL1.0668 mL2.1337 mL4.2674 mL
20mM0.1067 mL0.5334 mL1.0668 mL2.1337 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.