Bremelanotide Acetate

This product is for research use only, not for human use. We do not sell to patients.

Bremelanotide Acetate
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Size Price Stock
250mg$400Check With Us
500mg$650Check With Us
1g$975Check With Us

Cat #: V32521 CAS #: 1607799-13-2 Purity ≥ 99%

Description: Bremelanotide Acetate (PT-141; PT141; PT 141; Vyleesi), the acetatea salt of Bremelanotide, is a peptide analogue of alpha-MSH peptide acting as a melanocortin receptor agonist.

References: Pfaus JG, et al. Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10201-4.

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Molecular Weight (MW)1085.22
Molecular FormulaC52H72N14O12
CAS No.1607799-13-2
ProtocolIn VivoBremelanotide Acetate (50-200 μg/kg; s.c.; once) significantly increases proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers
Animal modelOvariectomized Long–Evans rats
Dosages50, 100, 200 μg/kg
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.9215 mL4.6074 mL9.2147 mL18.4294 mL
5mM0.1843 mL0.9215 mL1.8429 mL3.6859 mL
10mM0.0921 mL0.4607 mL0.9215 mL1.8429 mL
20mM0.0461 mL0.2304 mL0.4607 mL0.9215 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.