Caerulein (Caerulein; Cerulein; FI-6934)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1900 | Check With Us |
| 100mg | $3250 | Check With Us |
| 200mg | $4875 | Check With Us |
: Cat #: V12862 CAS #: 17650-98-5 Purity ≥ 99%
Description: Caerulein (Caerulein; Cerulein; FI-6934) is a novel, potent and specific decapeptide-based cholecystokinin receptor agonist, it is produced in the skin of Hila caerulea, an Australian amphibian.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 1352.41 |
|---|---|
| Molecular Formula | C58H73N13O21S2 |
| CAS No. | 17650-98-5 |
| Protocol | In Vitro | CeruLetide is chemically and biologically similar to the human gastrointestinal hormones cholecystokininin-pancreatin (CCK) and gastrin II. CeruLetide stimulates gallbladder contraction, exocrineal pancreas, gastric secretion, and motility in the distal duodenum, jejunum, ileum, and colon, while delaying gastric emptying and inhibiting the movement of the proximal duodenum |
|---|---|---|
| In Vivo | CeruLetide (0.4-0.5 micrograms/kg intravenously; 3-4 micrograms/kg subcutaneously) Causes vomiting and defecation in conscious intact dogs, 15-30 minutes after intravenous injection and after full recovery of SC administration after 2-4 hours. CeruLetide (5-15 ng/kg, iv) showed significant spasmodic effects on the pylorus in rats. CeruLetide can also lower blood pressure in anesthetized dogs |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.7394 mL | 3.6971 mL | 7.3942 mL | 14.7884 mL |
| 5mM | 0.1479 mL | 0.7394 mL | 1.4788 mL | 2.9577 mL |
| 10mM | 0.0739 mL | 0.3697 mL | 0.7394 mL | 1.4788 mL |
| 20mM | 0.0370 mL | 0.1849 mL | 0.3697 mL | 0.7394 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.