Nastorazepide (Z-360)

This product is for research use only, not for human use. We do not sell to patients.

Nastorazepide (Z-360)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1650Check With Us
500mg$2350Check With Us
1g$3525Check With Us

Cat #: V26248 CAS #: 209219-38-5 Purity ≥ 99%

Description: Nastorazepide, formerly known as Z-360, is a selective, orally bioavailable, 1,5-benzodiazepine-analogue gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity.

References: Kato H, et al. CCK-2/gastrin receptor signaling pathway is significant for gemcitabine-induced gene expression of VEGF in pancreatic carcinoma cells. Life Sci. 2011 Oct 24;89(17-18):603-8.

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Molecular Weight (MW)520.62
Molecular FormulaC29H36N4O5
CAS No.209219-38-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9208 mL9.6039 mL19.2079 mL38.4157 mL
5mM0.3842 mL1.9208 mL3.8416 mL7.6831 mL
10mM0.1921 mL0.9604 mL1.9208 mL3.8416 mL
20mM0.0960 mL0.4802 mL0.9604 mL1.9208 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.