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| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | Check With Us |
| 500mg | $1420 | Check With Us |
| 1g | $2130 | Check With Us |
: Cat #: V2944 CAS #: 84783-01-7 Purity ≥ 98%
Description: K-Ras-IN-1 (formerly known as K-Ras-Inhibitor-1) is a novel small molecule K-Ras inhibitor that binds to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure, in other words, K-Ras-IN-1 binds directly to K-Ras between switch I and switch II and inhibit Sos-catalyzed K-Ras activation.
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| Molecular Weight (MW) | 207.29 |
|---|---|
| Molecular Formula | C11H13NOS |
| CAS No. | 84783-01-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: ≥ 28 mg/mLr |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Solubility In Vivo | S=C(C1=CC=CC=C1O)N2CCCC2 |
| Synonyms | K-Ras-IN-1; K-Ras-IN1; K-Ras-IN 1; K-Ras Inhibitor-1; K-Ras Inhibitor 1 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.8242 mL | 24.1208 mL | 48.2416 mL | 96.4832 mL |
| 5mM | 0.9648 mL | 4.8242 mL | 9.6483 mL | 19.2966 mL |
| 10mM | 0.4824 mL | 2.4121 mL | 4.8242 mL | 9.6483 mL |
| 20mM | 0.2412 mL | 1.2060 mL | 2.4121 mL | 4.8242 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.