CID 44216842
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1050 | Check With Us |
| 500mg | $1700 | Check With Us |
| 1g | $2550 | Check With Us |
: Cat #: V2441 CAS #: 1222513-26-9 Purity ≥ 99%
Description: CID-44216842 is a novel and potent Cdc42-selective guanine nucleotide binding lead inhibitor.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 486.38 |
|---|---|
| Molecular Formula | C22H20BrN3O3S |
| CAS No. | 1222513-26-9 |
| Protocol | In Vitro | EC50: 1.0 μM (Cdc42 WT, in GTP binding assay) and 1.2 μM (Cdc42Q61L mutant, in GTP binding assay) |
|---|---|---|
| In Vivo | CID44216842 inhibits GTP binding to both Cdc42 and its mutant in a dose-dependent manner. The inhibition is specific toward Cdc42 with no effects on other GTPases including Rac and Rho in the same family |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0560 mL | 10.2800 mL | 20.5601 mL | 41.1201 mL |
| 5mM | 0.4112 mL | 2.0560 mL | 4.1120 mL | 8.2240 mL |
| 10mM | 0.2056 mL | 1.0280 mL | 2.0560 mL | 4.1120 mL |
| 20mM | 0.1028 mL | 0.5140 mL | 1.0280 mL | 2.0560 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.