Tiotropium bromide

This product is for research use only, not for human use. We do not sell to patients.

Tiotropium bromide
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Size Price Stock
250mg$315Check With Us
500mg$470Check With Us
1g$705Check With Us

Cat #: V15146 CAS #: 136310-93-5 Purity ≥ 99%

Description: Tiotropium Bromide (BA679BR; BA-679BR; PUR-0200; PUR0200; Spiriva) is an approved anticholinergic and bronchodilator medication used as a long-acting bronchodilator for the treatment of chronic obstructive pulmonary disease (COPD).

References: Barnes PJ. Tiotropium bromide. Expert Opin Investig Drugs. 2001 Apr;10(4):733-40.

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Product Promise

Promise
Molecular Weight (MW)472.42
Molecular FormulaC19H22BrNO4S2
CAS No.136310-93-5
ProtocolIn VitroTiotropium Bromide stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1168 mL10.5838 mL21.1676 mL42.3352 mL
5mM0.4234 mL2.1168 mL4.2335 mL8.4670 mL
10mM0.2117 mL1.0584 mL2.1168 mL4.2335 mL
20mM0.1058 mL0.5292 mL1.0584 mL2.1168 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.