ELAGOLIX

This product is for research use only, not for human use. We do not sell to patients.

ELAGOLIX
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1150Check With Us
500mg$1800Check With Us
1g$2700Check With Us

Cat #: V2801 CAS #: 834153-87-6 Purity ≥ 98%

Description: Elagolix (formerly NBI56418; ABT620; NBI-56418; ABT-620; trade name: Orilissa) is a potent, specific, orally bioavailable, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) used for pain management.

References: Carr B, et al. Elagolix, an oral GnRH antagonist, versus subcutaneous depot medroxyprogesterone acetate for the treatment of endometriosis: effects on bone mineral density. Reprod Sci. 2014 Nov;21(11):1341-1351.

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Product Promise

Promise
Molecular Weight (MW)631.59
Molecular FormulaC32H30F5N3O5
CAS No.834153-87-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mM in DMSOr
Water: < 1mg/mLr
Ethanol: < 1mg/mL
SynonymsABT-620; ABT 620; ABT620; NBI56418 Na; NBI-56418; NBI 56418; Elagolix sodium
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5833 mL7.9165 mL15.8331 mL31.6661 mL
5mM0.3167 mL1.5833 mL3.1666 mL6.3332 mL
10mM0.1583 mL0.7917 mL1.5833 mL3.1666 mL
20mM0.0792 mL0.3958 mL0.7917 mL1.5833 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.