Losartan D4 | CAS 1030937-27-9

Losartan D4

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10mg	$1550	To Be Confirmed
20mg	$2325	To Be Confirmed
50mg	$3490	To Be Confirmed

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Cat #: V34101 CAS #: 1030937-27-9 Purity ≥ 99%

Description: Losartan D4 (also called DuP753 D4; DuP-753 D4) is the tetra-deuterated form of losartan (Cozaar among others), which is an angiotensin II receptor antagonist and antihypertensive drug.

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Molecular Weight (MW)	3355.67
Molecular Formula	C151H228N40O47
CAS No.	1030937-27-9

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.2980 mL	1.4900 mL	2.9800 mL	5.9601 mL
5mM	0.0596 mL	0.2980 mL	0.5960 mL	1.1920 mL
10mM	0.0298 mL	0.1490 mL	0.2980 mL	0.5960 mL
20mM	0.0149 mL	0.0745 mL	0.1490 mL	0.2980 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.