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LY83583

This product is for research use only, not for human use. We do not sell to patients.

LY83583
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$550Check With Us
200mg$825Check With Us
500mg$1300Check With Us
email: [email protected]        [email protected]

Cat #: V24725 CAS #: 91300-60-6 Purity ≥ 99%

Description: LY83583 (LY 83583; LY-83583) is a novel and potent inhibitor of multple target proteins such as Msp1 and guanylate cyclase, also acts as a cGMP modulator that inhibits cGMP production. Reference: Naunyn-Schmiedeberg's archives of pharmacology, 1989, 340(1): 119-125.

References: Mülsch A, et al. LY 83583 (6-anilino-5,8-quinolinedione) blocks nitrovasodilator-induced cyclic GMP increases and inhibition of platelet activation. Naunyn Schmiedebergs Arch Pharmacol. 1989 Jul;340(1):119-25. 

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Molecular Weight (MW)250.25
Molecular FormulaC15H10N2O2
CAS No.91300-60-6
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9960 mL19.9800 mL39.9600 mL79.9201 mL
5mM0.7992 mL3.9960 mL7.9920 mL15.9840 mL
10mM0.3996 mL1.9980 mL3.9960 mL7.9920 mL
20mM0.1998 mL0.9990 mL1.9980 mL3.9960 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.