Fexofenadine

This product is for research use only, not for human use. We do not sell to patients.

Fexofenadine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$420Check With Us
10g$690Check With Us
20g$1035Check With Us

Cat #: V21005 CAS #: 83799-24-0 Purity ≥ 99%

Description: Fexofenadine (MDL-16455A; MDL16455A; Allegra; Terfenidine carboxylate; Telfast) is a histamine H1 receptor antagonist (antihistamine agent) approved for the treatment of allergy symptoms such as hay fever, nasal congestion, and urticaria.

References: Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75.

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Molecular Weight (MW)501.66
Molecular FormulaC32H39NO4
CAS No.83799-24-0
ProtocolIn VivoFexofenadine hydrochloride (oral administration; 5-20 mg/kg; once daily; 3 w) suppresses both eosinophilia and systemic anaphylaxis in C57BL/6 mice infected with T. spiralis
Animal modelC57BL/6 mice infected with Trichinella spiralis
Dosages5, 10 and 20 mg/kg
AdministrationOral administration; 5, 10 and 20 mg/kg; once daily; 3 weeks
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9934 mL9.9669 mL19.9338 mL39.8676 mL
5mM0.3987 mL1.9934 mL3.9868 mL7.9735 mL
10mM0.1993 mL0.9967 mL1.9934 mL3.9868 mL
20mM0.0997 mL0.4983 mL0.9967 mL1.9934 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.