JNJ-31001074

This product is for research use only, not for human use. We do not sell to patients.

JNJ-31001074
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1450To Be Confirmed
500mg$2080To Be Confirmed
1g$3120To Be Confirmed

Cat #: V4515 CAS #: 929622-08-2(free base) Purity ≥ 98%

Description: Bavisant (also known as JNJ-31001074) is a novel, highly selective, orally bioactive antagonist of the human H3 receptor with a novel mechanism of action which involves wakefulness and cognition.

References: Ghamari N, et al. Histamine H3 receptor antagonists/inverse agonists: Where do they go? Pharmacol Ther. 2019 Aug;200:69-84

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Product Promise

Promise
Molecular Weight (MW)329.44
Molecular FormulaC19H27N3O2
CAS No.929622-08-2(free base)
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VivoBavisant increases acetylcholine levels in rat frontal cortex
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0355 mL15.1773 mL30.3545 mL60.7091 mL
5mM0.6071 mL3.0355 mL6.0709 mL12.1418 mL
10mM0.3035 mL1.5177 mL3.0355 mL6.0709 mL
20mM0.1518 mL0.7589 mL1.5177 mL3.0355 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.