Nizatidine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $150 | Check With Us |
| 25g | $280 | Check With Us |
| 50g | $420 | Check With Us |
: Cat #: V1219 CAS #: 76963-41-2 Purity ≥ 98%
Description: Nizatidine (Tazac, Axid, LY-139037, LY 139037, LY139037) is a potent histamine H2 receptor antagonist used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
References:
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 331.46 |
|---|---|
| Molecular Formula | C12H21N5O2S2 |
| CAS No. | 76963-41-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 66 mg/mL (199.1 mM)r |
| Water: 28 mg/mL (84.5 mM)r | |
| Ethanol: 18 mg/mL (54.3 mM) | |
| Solubility In Vivo | Saline: 30 mg/mL |
| Synonyms | LY 139037, Tazac, Axid, LY-139037, LY139037 |
| Protocol | In Vivo | Nizatidine (oral gavage; 27 mg/kg; once daily; 4 weeks) decreases the incidence of gastric ulceration, and significantly decreases the mean ulcer score and ulcer index in male albino rats |
|---|---|---|
| Animal model | Male albino rats | |
| Dosages | 27 mg/kg | |
| Administration | Oral gavage; 27 mg/kg; once daily; 4 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0170 mL | 15.0848 mL | 30.1696 mL | 60.3391 mL |
| 5mM | 0.6034 mL | 3.0170 mL | 6.0339 mL | 12.0678 mL |
| 10mM | 0.3017 mL | 1.5085 mL | 3.0170 mL | 6.0339 mL |
| 20mM | 0.1508 mL | 0.7542 mL | 1.5085 mL | 3.0170 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.