BAY-38-7271
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25mg | $1250 | Check With Us |
| 50mg | $1875 | Check With Us |
| 100mg | $2810 | Check With Us |
: Cat #: V3361 CAS #: 212188-60-8 Purity ≥ 98%
Description: BAY-38-7271 is novel, potent, highly selective cannabinoid receptor agonist with the potential for the treatment of traumatic brain injury.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 430.44 |
|---|---|
| Molecular Formula | C20H21F3O5S |
| CAS No. | 212188-60-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent |
| Protocol | In Vitro | BAY 38-7271 shows only minor interactions at the micromolar range with other binding sites such as adenosine A3 receptor (IC50 = 7.5 μM), peripheral GABAA benzodiazepine receptor (IC50 = 971 nM), melatonin ML1 receptor (IC50 = 3.3 μM), and at the monoamine transporter (IC50 = 1.7 μM) |
|---|---|---|
| In Vivo | BAY 38-7271 (Ed50 = 0.02 mg/kg; i.v. and 0.5 mg/kg; i.p.) induces a potent and dose-de-pendent reduction in core body temperature | |
| Animal model | Wistar rat ,TBI rat models (acute subdural hematoma, SDH) | |
| Dosages | 1 ng/kg/h, 10 ng/kg/h, 100 ng/kg/h, 1000 ng/kg/h | |
| Administration | Intravenous infusion, for 4 hours |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3232 mL | 11.6160 mL | 23.2320 mL | 46.4641 mL |
| 5mM | 0.4646 mL | 2.3232 mL | 4.6464 mL | 9.2928 mL |
| 10mM | 0.2323 mL | 1.1616 mL | 2.3232 mL | 4.6464 mL |
| 20mM | 0.1162 mL | 0.5808 mL | 1.1616 mL | 2.3232 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.