RO 46-8443
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1200 | Check With Us |
| 500mg | $1700 | Check With Us |
| 1g | $2550 | Check With Us |
: Cat #: V3337 CAS #: 175556-12-4 Purity ≥ 98%
Description: RO 46-8443 is a novel, potent, selective and non-peptidic antagonist of the endothelin ETB receptor.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 609.69 |
|---|---|
| Molecular Formula | C31H35N3O8S |
| CAS No. | 175556-12-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | COC(C=CC=C1)=C1OC2=C(OCC(O)CO)N=C(C3=CC=C(OC)C=C3)N=C2NS(C4=CC=C(C(C)(C)C)C=C4)(=O)=O |
| Synonyms | RO 468443; RO-468443; RO468443; RO 46,8443; RO-46,8443; RO46,8443; RO 46-8443; RO46-8443; RO-46-8443 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6402 mL | 8.2009 mL | 16.4018 mL | 32.8036 mL |
| 5mM | 0.3280 mL | 1.6402 mL | 3.2804 mL | 6.5607 mL |
| 10mM | 0.1640 mL | 0.8201 mL | 1.6402 mL | 3.2804 mL |
| 20mM | 0.0820 mL | 0.4100 mL | 0.8201 mL | 1.6402 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.