Home > Signaling Pathways>GPCR & G Protein>S1P Receptor>PF-429242
PF-429242

This product is for research use only, not for human use. We do not sell to patients.

PF-429242
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1250Check With Us
1g$1875Check With Us
email: [email protected]        [email protected]

Cat #: V4144 CAS #: 947303-87-9 Purity ≥ 98%

Description: PF429242 (PF-429242) is a novel, potent, reversible and competitive S1P [sterol regulatory element-binding protein (SREBP) site 1 protease] inhibitor with an IC50 of 170 nM.

References: J Pharmacol Exp Ther. 2008 Sep;326(3):801-8.; Viruses. 2016 Feb 10;8(2). pii: E46.; J Virol. 2011 Jan;85(2):795-803.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)409.57
Molecular FormulaC25H35N3O2
CAS No.947303-87-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4416 mL12.2079 mL24.4159 mL48.8317 mL
5mM0.4883 mL2.4416 mL4.8832 mL9.7663 mL
10mM0.2442 mL1.2208 mL2.4416 mL4.8832 mL
20mM0.1221 mL0.6104 mL1.2208 mL2.4416 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.