Home > Signaling Pathways>GPCR & G Protein>PAFR>Ginkgolide B (BN-52021)
Ginkgolide B (BN-52021)

This product is for research use only, not for human use. We do not sell to patients.

Ginkgolide B (BN-52021)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$450Check With Us
500mg$700Check With Us
1g$1050Check With Us

Cat #: V1493 CAS #: 15291-77-7 Purity ≥ 98%

Description: Ginkgolide B (Bilobalide B; BN-52051; BN52051) is a naturally occuring compound acting as a PAFR (platelet-activating factor receptor) antagonist with an IC50 of 3.6 μM.

References: Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)424.4
Molecular FormulaC20H24O10
CAS No.15291-77-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 85 mg/mL (200.3 mM)r
Water:<1 mg/mLr
Ethanol: 2 mg/mL (4.9 mM)
Solubility In Vivo30% Propylene glycol, 5% Tween 80, 65% D5W: 10mg/mL
SynonymsBN-52021; Bilobalide B; BN 52051; BN52051; Ginkgolide B
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3563 mL11.7813 mL23.5627 mL47.1254 mL
5mM0.4713 mL2.3563 mL4.7125 mL9.4251 mL
10mM0.2356 mL1.1781 mL2.3563 mL4.7125 mL
20mM0.1178 mL0.5891 mL1.1781 mL2.3563 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.