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MSX-130

This product is for research use only, not for human use. We do not sell to patients.

MSX-130
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Size Price Stock
50mg$500Check With Us
100mg$800Check With Us
200mg$1200Check With Us
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Cat #: V26051 CAS #: 4051-59-6 Purity ≥ 99%

Description: MSX-130 is novel and potent CXCR4 (Chemokine Receptor 4) inhibitor/antagonist with anticancer activity.

References: Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64.

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Molecular Weight (MW)514.62
Molecular FormulaC36H26N4
CAS No.4051-59-6
ProtocolIn VitroThe C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9432 mL9.7159 mL19.4318 mL38.8636 mL
5mM0.3886 mL1.9432 mL3.8864 mL7.7727 mL
10mM0.1943 mL0.9716 mL1.9432 mL3.8864 mL
20mM0.0972 mL0.4858 mL0.9716 mL1.9432 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.