PS372424 HCl

This product is for research use only, not for human use. We do not sell to patients.

PS372424 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$990To Be Confirmed
100mg$1450To Be Confirmed
200mg$2175To Be Confirmed

Cat #: V13316 CAS #: 914291-61-5 Purity ≥ 99%

Description: PS372424 (PS-372424) HCl is a novel and potent agonist of CXCR3 with anti-inflammatory activity.

References: Boyé K, et al. The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors. Nat Commun. 2017 Nov 17;8(1):1571.

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Product Promise

Promise
Molecular Weight (MW)588.74
Molecular FormulaC33H44N6O4
CAS No.914291-61-5
ProtocolIn VitroPS372424 (100 ng/mL) increases p-Erk1 and p-Erk2 in U87-CXCR3-A cells after 5 min of stimulation
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6985 mL8.4927 mL16.9854 mL33.9709 mL
5mM0.3397 mL1.6985 mL3.3971 mL6.7942 mL
10mM0.1699 mL0.8493 mL1.6985 mL3.3971 mL
20mM0.0849 mL0.4246 mL0.8493 mL1.6985 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.