SRT3190

This product is for research use only, not for human use. We do not sell to patients.

SRT3190
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1200Check With Us
250mg$2100Check With Us
500mg$3150Check With Us

Cat #: V3797 CAS #: 1204707-73-2 Purity ≥ 98%

Description: SRT3190 (SRT-3190) is a potent and selective antagonist of CXCR2 (C-X-C chemokine receptor type 2) and an activator of SIRT1 with anti-Inflammatory and immunomodulatory activity.

References: Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases. WO2010007427A1

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Molecular Weight (MW)475.53
Molecular FormulaC18H23F2N5O4S2
CAS No.1204707-73-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mMr
Water: < 1 mg/mLr
Ethanol: < 1 mg/mL
SynonymsSRT-3190; SRT3190; SRT 3190.
ProtocolIn VitroSRT3190 (Reference Example 2) is an antagonist of CXCR2, used in the research of chemokine mediated diseases
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1029 mL10.5146 mL21.0292 mL42.0583 mL
5mM0.4206 mL2.1029 mL4.2058 mL8.4117 mL
10mM0.2103 mL1.0515 mL2.1029 mL4.2058 mL
20mM0.1051 mL0.5257 mL1.0515 mL2.1029 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.