Home > Signaling Pathways>GPCR & G Protein>Adenosine Receptor>Namodenoson (2 Cl-IB-MECA; CF102)
Namodenoson (2 Cl-IB-MECA; CF102)

This product is for research use only, not for human use. We do not sell to patients.

Namodenoson (2 Cl-IB-MECA; CF102)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$2050Check With Us
500mg$3250Check With Us
1g$4875Check With Us

Cat #: V17958 CAS #: 163042-96-4 Purity ≥ 98%

Description: Namodenoson (2-Cl-IB-MECA; CF102; CF-102) is a novel, potent, orally bioavailable, and highly selective adenosine A3 receptor (A3AR) agonist with potential anticancer activity.

References: Van Schaick EA et al. Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur J Pharmacol. 1996 Jul 25;308(3):311-4.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)544.73
Molecular FormulaC18H18ClIN6O4
CAS No.163042-96-4
ProtocolIn VivoIntravenous administration of 200 μg/kg Namodenoson (2-Cl-IB-MECA) resulted in a short-lasting hypotension, which was accompanied by a 50-100-fold increase in plasma histamine concentrations. Administration of a second dose of Namodenoson (2-Cl-IB-MECA) did not elicit any hemodynamic effects
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8358 mL9.1789 mL18.3577 mL36.7154 mL
5mM0.3672 mL1.8358 mL3.6715 mL7.3431 mL
10mM0.1836 mL0.9179 mL1.8358 mL3.6715 mL
20mM0.0918 mL0.4589 mL0.9179 mL1.8358 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.