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CAY10683 (Santacruzamate A)

This product is for research use only, not for human use. We do not sell to patients.

CAY10683 (Santacruzamate A)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$550Check With Us
500mg$850Check With Us
1g$1275Check With Us

Cat #: V2867 CAS #: 1477949-42-0 Purity ≥ 98%

Description: Santacruzamate A (also known as CAY10683) is a potent and selective inhibitor of HDAC (histone deacetylase) with IC50 of 119 pM for HDAC2, it exhibits >3600-fold selectivity over other HDACs.

References: Pavlik CM,et al. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J Nat Prod. 2013 Nov 22;76(11):2026-33.

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Product Promise

Promise
Molecular Weight (MW)278.35
Molecular FormulaC15H22N2O3
CAS No.1477949-42-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 55 mg/mLr
Water: <1 mg/mLr
Ethanol: 55 mg/mL
SMILES CodeO=C(NCCC1=CC=CC=C1)CCCNC(OCC)=O
SynonymsSantacruzamate A; CAY10683; CAY-10683; CAY 10683
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5926 mL17.9630 mL35.9260 mL71.8520 mL
5mM0.7185 mL3.5926 mL7.1852 mL14.3704 mL
10mM0.3593 mL1.7963 mL3.5926 mL7.1852 mL
20mM0.1796 mL0.8981 mL1.7963 mL3.5926 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.