Elevenostat

This product is for research use only, not for human use. We do not sell to patients.

Elevenostat
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$650To Be Confirmed
500mg$1050To Be Confirmed
1g$1575To Be Confirmed

Cat #: V50034 CAS #: 1454902-97-6 Purity ≥ 99%

Description: Elevenostat (JB3-22) is a potent HDAC11 inhibitor (IC50=0.235 µM) with anticancer and anti-multiple myeloma (MM) activity.

References: Huang J, et al. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Sci Rep. 2017;7(1):8626. Published 2017 Aug 17.

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Molecular Weight (MW)315.32
Molecular FormulaC16H17N3O4
CAS No.1454902-97-6
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1714 mL15.8569 mL31.7138 mL63.4276 mL
5mM0.6343 mL3.1714 mL6.3428 mL12.6855 mL
10mM0.3171 mL1.5857 mL3.1714 mL6.3428 mL
20mM0.1586 mL0.7928 mL1.5857 mL3.1714 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.