Ifosfamide | CAS 3778-73-2

Ifosfamide

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
2g	$250	Check With Us
5g	$450	Check With Us
10g	$675	Check With Us

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Cat #: V1445 CAS #: 3778-73-2 Purity ≥ 98%

Description: Ifosfamide (formerly NSC-109724, Isophosphamide; Ifomide; Iphosphamid; iphosphamide; Isoendoxan; IsoEndoxan; Naxamide; Cyfos; Ifex; Ifosfamidum) is an approved anticancer medication which acts as a nitrogen mustard and DNA alkylating agent/alkylator.

References: Helal M. Prenatal effects of transplacental exposure to ifosfamide in rats. Biotech Histochem. 2016 Jul;91(5):357-68.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	261.09
Molecular Formula	C7H15Cl2N2O2P
CAS No.	3778-73-2
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 52 mg/mL (199.2 mM)r
	Water: 52 mg/mL (199.2 mM)r
	Ethanol: 52 mg/mL (199.2 mM)
Synonyms	NSC-109724; Isophosphamide; Ifomide; NSC 109724; NSC109724; Iphosphamid; iphosphamide; Isoendoxan; IsoEndoxan; isophosphamide; Naxamide; Trade names: Cyfos; Ifex; Ifosfamidum.

Protocol	In Vitro	Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors
Protocol	In Vivo	Ifosfamide (50 mg/kg, i.p.) treatment before mating increases percentage of post-implantation loss and resorbs fetuses in pregnant rats. Ifosfamide also (50 mg/kg, i.p.) decreases the progesterone in the serum of pregnant rats. However, Ifosfamide causes no obvious difference with the control rats at 25 mg/kg. Ifosfamide (25, 50 mg/kg, i.p.) induces apoptosis and histological changes in the placentas and prenatal rats, most sensitive fetal organs are the brain, liver and kidney

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.8301 mL	19.1505 mL	38.3010 mL	76.6019 mL
5mM	0.7660 mL	3.8301 mL	7.6602 mL	15.3204 mL
10mM	0.3830 mL	1.9150 mL	3.8301 mL	7.6602 mL
20mM	0.1915 mL	0.9575 mL	1.9150 mL	3.8301 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.