Alovudine

This product is for research use only, not for human use. We do not sell to patients.

Alovudine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$250Check With Us
500mg$400Check With Us
1g$600Check With Us

Cat #: V4727 CAS #: 25526-93-6 Purity ≥ 98%

Description: Alovudine (MIV310; CL-184824; 3'-Fluoro-3'-deoxythymidine) is a novel and potent reverse transcriptase inhibitor (RTI) with the potential for the treatment of HIV infection.

References: Challapalli A, et al. 3'-Deoxy-3'-18F-fluorothymidine positron emission tomography as an early predictor of disease progression in patients with advanced and metastatic pancreatic cancer. Eur J Nucl Med Mol Imaging. 2015 May;42(6):831-40.

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Product Promise

Promise
Molecular Weight (MW)244.22
Molecular FormulaC10H13FN2O4
CAS No.25526-93-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.0947 mL20.4733 mL40.9467 mL81.8934 mL
5mM0.8189 mL4.0947 mL8.1893 mL16.3787 mL
10mM0.4095 mL2.0473 mL4.0947 mL8.1893 mL
20mM0.2047 mL1.0237 mL2.0473 mL4.0947 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.