Mechlorethamine HCl

This product is for research use only, not for human use. We do not sell to patients.

Mechlorethamine HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$150Check With Us
2g$250Check With Us
5g$375Check With Us

Cat #: V1442 CAS #: 55-86-7 Purity ≥ 98%

Description: Mechlorethamine HCl (chloramin; chlorethamine; mustine, HN2, Mustargen; and embikhin), the hydrochloride salt of Mechlorethamine, is the prototype of a class of anticancer chemotherapeutic drugs called DNA alkylators or DNA alkylating agents.

References: Cao Z, et al. Effect of brentuximab vedotin combined with chlormethine hydrochloride on the treatment of 6 patients with relapsed and refractory Hodgkin lymphoma. Zhonghua Xue Ye Xue Za Zhi. 2015 Jul 14;36(7):575-577.

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Product Promise

Promise
Molecular Weight (MW)192.51
Molecular FormulaC5H11Cl2N.HCl
CAS No.55-86-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 39 mg/mL (202.6 mM)r
Water: 39 mg/mL (202.6 mM)r
Ethanol: 39 mg/mL (202.6 mM)
SynonymsMechlorethamine hydrochloride; chloramin; chlorethamine HCl; chlorethamine hydrochloride
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.1945 mL25.9727 mL51.9454 mL103.8907 mL
5mM1.0389 mL5.1945 mL10.3891 mL20.7781 mL
10mM0.5195 mL2.5973 mL5.1945 mL10.3891 mL
20mM0.2597 mL1.2986 mL2.5973 mL5.1945 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.