Sorivudine

This product is for research use only, not for human use. We do not sell to patients.

Sorivudine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$600Check With Us
100mg$990Check With Us
200mg$1480Check With Us

Cat #: V15074 CAS #: 77181-69-2 Purity ≥ 99%

Description: Sorivudine (BV-araU; Bravavir; ARYS-01; SQ-32756; BVAU; JA-001; YN-72; DRU-0136) is a novel and potent DNA polymerase inhibitor with the potential to be used for the treatment of herpes zoster (shingles).

References: Diasio RB, et al. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase. Br J Clin Pharmacol. 1998 Jul;46(1):1-4.

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Product Promise

Promise
Molecular Weight (MW)349.13
Molecular FormulaC11H13BrN2O6
CAS No.77181-69-2
ProtocolIn VitroSorivudine (BV-araU) inhibits strains of HSV-1 and HSV-2 (wild-type strains VR-3 and UW-268) with ID50s (50% inhibitory dose) of 0.39 and 0.67 μM, respectively
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8643 mL14.3213 mL28.6426 mL57.2853 mL
5mM0.5729 mL2.8643 mL5.7285 mL11.4571 mL
10mM0.2864 mL1.4321 mL2.8643 mL5.7285 mL
20mM0.1432 mL0.7161 mL1.4321 mL2.8643 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.