Vidarabine (Ara-A)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25g	$380	Check With Us
50g	$650	Check With Us
100g	$975	Check With Us

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Cat #: V1460 CAS #: 5536-17-4 Purity ≥ 98%

Description: Vidarabine (Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine; Arabinofuranosyladenine) is an approved antiviral drug that interfers with the synthesis of viral DNA, and is mainly used to treat HSV and VZV: herpes simplex and varicella zoster viruses

References: Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	267.24
Molecular Formula	C10H13N5O4
CAS No.	5536-17-4
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 53 mg/mL (198.3 mM)r
	Water: 3 mg/mL (11.2 mM)r
	Ethanol: <1 mg/mL
Synonyms	Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine; Vira A; Vira-A; ViraA; Ara-A; Ara A; Arabinofuranosyladenine; 9-beta-Arabinofuranosyladenine; Vidarabine.

Protocol	In Vitro	Vidarabine (Ara-A) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.7420 mL	18.7098 mL	37.4195 mL	74.8391 mL
5mM	0.7484 mL	3.7420 mL	7.4839 mL	14.9678 mL
10mM	0.3742 mL	1.8710 mL	3.7420 mL	7.4839 mL
20mM	0.1871 mL	0.9355 mL	1.8710 mL	3.7420 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.