Flunarizine 2HCl

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$200	Check With Us
5g	$380	Check With Us
10g	$570	Check With Us

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Cat #: V1447 CAS #: 22348-32-9 Purity ≥ 98%

Description: Flunarizine 2HCl (formerly R-14950; KW3149; R14950; KW 3149; trade name Sibelium), the dihydrochloride salt form of Flunarizine, is a selective calcium entry/channel blocker with calmodulin binding properties and anti-histamine H1 activity.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	477.42
Molecular Formula	C26H26F2N2.2HCl
CAS No.	22348-32-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 5 mg/mL (10.5 mM)r
	Water: <1 mg/mLr
	Ethanol: 3 mg/mL (6.3 mM)
Synonyms	KW-3149; R-14950; KW3149; R14950; KW 3149; R 14950

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0946 mL	10.4730 mL	20.9459 mL	41.8918 mL
5mM	0.4189 mL	2.0946 mL	4.1892 mL	8.3784 mL
10mM	0.2095 mL	1.0473 mL	2.0946 mL	4.1892 mL
20mM	0.1047 mL	0.5236 mL	1.0473 mL	2.0946 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.