Novobiocin Sodium (Albamycin; Cathomycin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $600 | Check With Us |
| 10g | $990 | Check With Us |
| 20g | $1490 | Check With Us |
: Cat #: V1414 CAS #: 1476-53-5 Purity ≥ 98%
Description: Novobiocin Sodium (formerly known as U6591, U-6591, Cathomycin, Inabiocin, Albadry, Streptonivicin, Albamycin) is a novel and potent antibiotic of the aminocoumarin class isolated from Streptomyces niveus and used for bacterial infections.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 634.61 |
|---|---|
| Molecular Formula | C31H35N2O11.Na |
| CAS No. | 1476-53-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 127 mg/mL (200.1 mM)r |
| Water: 127 mg/mL (200.1 mM)r | |
| Ethanol: 127 mg/mL (200.1 mM) | |
| Synonyms | U 6591, Albadry, Albamycin, Novobiocin sodium salt, Sodium albamycin, Sodium novobiocin, U6591, U-6591, Novobiocin monosodium salt, Cardelmycin sodium salt, Cathomycin, Inabiocin, Monosodium novobiocin, Novobiocin sodium, Novobiocin monosodium, Novobiocin natrium, Streptonivicin sodium salt, Vulcamycin |
| Protocol | In Vitro | Novobiocin sodium (1 mM) competitively inhibits ATP binding to gyrase B to interfere with nucleotide binding and interferes with the association of the co-chaperones Hsc70 and p23 with Hsp90 |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.5758 mL | 7.8789 mL | 15.7577 mL | 31.5154 mL |
| 5mM | 0.3152 mL | 1.5758 mL | 3.1515 mL | 6.3031 mL |
| 10mM | 0.1576 mL | 0.7879 mL | 1.5758 mL | 3.1515 mL |
| 20mM | 0.0788 mL | 0.3939 mL | 0.7879 mL | 1.5758 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.