Gatifloxacin (AM-1155)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$250	Check With Us
50g	$750	Check With Us
100g	$1125	Check With Us

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Cat #: V1399 CAS #: 112811-59-3 Purity ≥ 98%

Description: Gatifloxacin (formerly also known as AM-1155, CG5501, BMS-206584; PD135432; Tequin; Zymar; Gatiflo; Zymaxid; AM 1155) is a fourth-generation antibiotic of the fluoroquinolone family used to treat tuberculosis and pneumonia, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	375.39
Molecular Formula	C19H22FN3O4
CAS No.	112811-59-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 7 mg/mL (18.6 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Synonyms	AM-1155, CG5501, BMS-206584; BMS 206584-01; PD 135432; BMS 206584-01; PD-135432; BMS206584-01; PD135432; Tequin; Zymar; Gatiflo; Zymaxid; AM 1155; AM-1155; BMS-206584; CG 5501; gatifloxacin; gatifloxacine; Tequin; Zymar

Protocol	In Vivo	Gatifloxacin (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis
	Animal model	Female BALB/c mice with Nocardia brasiliensis in the right hind footpad.
	Dosages	100 mg/kg
	Administration	Subcutaneous injection; 3 times a day; 30 days

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.6639 mL	13.3195 mL	26.6390 mL	53.2779 mL
5mM	0.5328 mL	2.6639 mL	5.3278 mL	10.6556 mL
10mM	0.2664 mL	1.3319 mL	2.6639 mL	5.3278 mL
20mM	0.1332 mL	0.6660 mL	1.3319 mL	2.6639 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.