Daunorubicin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $850 | Check With Us |
| 1g | $1350 | Check With Us |
| 5g | $3645 | Check With Us |
: Cat #: V4896 CAS #: 20830-81-3 (free base) Purity ≥ 98%
Description: Daunorubicin (also know as Daunomycin; RP 13057; Rubidomycin), an anthracycline analogue and a topoisomerase II inhibitor is mainly used as an antibiotic.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 527.53 |
|---|---|
| Molecular Formula | C27H29NO10 |
| CAS No. | 20830-81-3 (free base) |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMrr |
| Water: N/Arr | |
| Ethanol: <1 mg/mL | |
| Synonyms | Daunomycin HCl; RP 13057; Rubidomycin; RP-13057; RP13057; Daunomycin hydrochloride; daunomycin HCl; daunorubidomycine; US brand names: Cerubidine; Rubidomycin; Foreign brand names: Cerubidin; Daunoblastin; Daunoblastina; Ondena; Rubilem; Abbreviations: DNM; DNR; DRB; Code names: FI6339; RP13057. |
| Protocol | In Vivo | Daunorubicin (intravenous injection, 3 mg/kg, three times at 48 h intervals.) produces cardiotoxicity and nephrotoxicity in rats |
|---|---|---|
| Animal model | Male Sprague-Dawley rats | |
| Dosages | 3 mg/kg | |
| Administration | Intravenous injection, three times at 48 h intervals. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8956 mL | 9.4781 mL | 18.9563 mL | 37.9125 mL |
| 5mM | 0.3791 mL | 1.8956 mL | 3.7913 mL | 7.5825 mL |
| 10mM | 0.1896 mL | 0.9478 mL | 1.8956 mL | 3.7913 mL |
| 20mM | 0.0948 mL | 0.4739 mL | 0.9478 mL | 1.8956 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.