Doxorubicin

This product is for research use only, not for human use. We do not sell to patients.

Doxorubicin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$250Check With Us
1g$450Check With Us
5g$1215Check With Us

Cat #: V2644 CAS #: 23214-92-8 Purity ≥ 98%

Description: Doxorubicin (Adriamycin; NSC-123127; FI-106; Adriblastine; Adrimedac) is a naturally occuring anthracycline antibiotic isolated from the bacterium Streptomyces peucetius var.

References: Sadeghi-Aliabadi H, et al. Cytotoxic evaluation of doxorubicin in combination with simvastatin against human cancer cells. Res Pharm Sci. 2010 Jul;5(2):127-33.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)543.52
Molecular FormulaC27H29NO11
CAS No.23214-92-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 20 mg/mL (34.48 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsAdriamycin; Hydroxydaunorubicin; ADR; DOX. Code name: FI106; chloridrato de doxorrubicina. Adriamycin; Adriacin; Adriblastina; Adriblastine; Adrimedac; DOXOCELL; Doxolem; Doxorubin; Farmiblastina; Rubex. Abbreviations: ADM; Adria;
ProtocolIn VitroCombination of Doxorubicin (Hydroxydaunorubicin) and Simvastatin in the highest tested concentrations (2 μM and 10 μM, respec-tively) kills 97% of the Hela cells
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8399 mL9.1993 mL18.3986 mL36.7972 mL
5mM0.3680 mL1.8399 mL3.6797 mL7.3594 mL
10mM0.1840 mL0.9199 mL1.8399 mL3.6797 mL
20mM0.0920 mL0.4600 mL0.9199 mL1.8399 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.