Bucladesine calcium (DC2797)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $500 | Check With Us |
| 2g | $850 | Check With Us |
| 5g | $1275 | Check With Us |
: Cat #: V4272 CAS #: 938448-87-4 Purity ≥ 98%
Description: Bucladesine calcium (Dibutyryl-cAMP calcium; DC2797 calcium salt) is a cell-permeable PKA activator/agonist and a cAMP analog that mimics the action of endogenous cAMP.
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| Molecular Weight (MW) | 488.42 |
|---|---|
| Molecular Formula | C₁₈H₂₃Ca₀.₅N₅O₈P |
| CAS No. | 938448-87-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >100 mg/mLr |
| Water: >100 mg/mLr | |
| Ethanol: N/A | |
| Solubility In Vivo | 10% DMSO+ddH2O: 30 mg/mL |
| Synonyms | dbcAMP; Dibutyryl-cAMP calcium salt; DC2797; DC-2797; DC 2797; calcium dibutyryl cAMP; Bucladesine sodium; DbcAMP calcium; Actosin; calcium Dibutyryl cAMP; Cyclic dibutyryl-AMP calcium salt |
| Protocol | In Vitro | Bucladesine (bilateral infusion of 10 mM or 100 mM) leads to a significant reduction in escape latency and travel distance (showing an improvement in spatial memory) compared to the control, as assesed by Morris water maze task in male rats. Bucladesine at 1 mM and 5 mM concentrations infused within minutes after 0.5 mg nicotine infusion improves spatial memory retention in male rats |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0474 mL | 10.2371 mL | 20.4742 mL | 40.9484 mL |
| 5mM | 0.4095 mL | 2.0474 mL | 4.0948 mL | 8.1897 mL |
| 10mM | 0.2047 mL | 1.0237 mL | 2.0474 mL | 4.0948 mL |
| 20mM | 0.1024 mL | 0.5119 mL | 1.0237 mL | 2.0474 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.