VL285
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $1150 | Check With Us |
500mg | $1700 | Check With Us |
1g | $2550 | Check With Us |
Cat #: V28020 CAS #: 1448188-57-5 Purity ≥ 99%
Description: VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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Molecular Weight (MW) | 532.65 |
---|---|
Molecular Formula | C29H32N4O4S |
CAS No. | 1448188-57-5 |
Protocol | In Vitro | Treatment with VL285 attenuates the ability of HaloPROTAC3 to induce the degradation of GFP-HaloTag7 |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.8774 mL | 9.3870 mL | 18.7741 mL | 37.5481 mL |
5mM | 0.3755 mL | 1.8774 mL | 3.7548 mL | 7.5096 mL |
10mM | 0.1877 mL | 0.9387 mL | 1.8774 mL | 3.7548 mL |
20mM | 0.0939 mL | 0.4694 mL | 0.9387 mL | 1.8774 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.