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MNS (NSC 170724, MDBN)

This product is for research use only, not for human use. We do not sell to patients.

MNS (NSC 170724, MDBN)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100g$450Check With Us
200g$700Check With Us
500g$1050Check With Us

Cat #: V1320 CAS #: 1485-00-3 Purity ≥ 98%

Description: MNS (NSC170724; NSC-170724; NSC 170724; 5-(2-Nitrovinyl)benzodioxole)) is a novel, potent and selective TKI-tyrosine kinase inhibitor with anti-platelet activity.

References: Wang WY, et al. Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity. Biochem Pharmacol. 2007;74(4):601-611.

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Product Promise

Promise
Molecular Weight (MW)193.16
Molecular FormulaC9H7NO4
CAS No.1485-00-3
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 39 mg/mL (201.9 mM)rr
Water: <1 mg/mLrr
Ethanol: <1 mg/mL
Solubility In Vivo2% DMSO+corn oil: 5mg/mL
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.1771 mL25.8853 mL51.7706 mL103.5411 mL
5mM1.0354 mL5.1771 mL10.3541 mL20.7082 mL
10mM0.5177 mL2.5885 mL5.1771 mL10.3541 mL
20mM0.2589 mL1.2943 mL2.5885 mL5.1771 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.