Dasotraline

This product is for research use only, not for human use. We do not sell to patients.

Dasotraline
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1050Check With Us
500mg$1750Check With Us
1g$2625Check With Us

Cat #: V29672 CAS #: 675126-05-3 Purity ≥ 99%

Description: Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 of 4, 6, and 11 nM, respectively.

References: Guiard BP, et al. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23.

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Molecular Weight (MW)328.661
Molecular FormulaC₁₆H₁₅Cl₂N
CAS No.675126-05-3
SynonymsSEP 225289
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0426 mL15.2132 mL30.4265 mL60.8530 mL
5mM0.6085 mL3.0426 mL6.0853 mL12.1706 mL
10mM0.3043 mL1.5213 mL3.0426 mL6.0853 mL
20mM0.1521 mL0.7607 mL1.5213 mL3.0426 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.