This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $550 | Check With Us |
| 500mg | $850 | Check With Us |
| 1g | $1275 | Check With Us |
: Cat #: V2290 CAS #: 218457-67-1 Purity ≥ 99%
Description: CB-103 is a novel and potent γ-secretase inhibitor that is currently being investigated in Phase-1 dose escalation in cancer patients.
References: CB-103 inhibits NOTCH dependent cellular processes in mice
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 242.322 |
|---|---|
| Molecular Formula | C15H18N2O |
| CAS No. | 218457-67-1 |
| SMILES Code | CC(C)(C)C1=CC=C(C=C1)OC2=NC=C(C=C2)N |
| Synonyms | CB 103; CB-103; CB103 |
| Protocol | In Vitro | CB-103 acts as a pan-NOTCH inhibitor by targeting NOTCH transcriptional activation complex |
|---|---|---|
| In Vivo | CB-103 inhibits NOTCH dependent cellular processes in mice |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.1267 mL | 20.6337 mL | 41.2674 mL | 82.5348 mL |
| 5mM | 0.8253 mL | 4.1267 mL | 8.2535 mL | 16.5070 mL |
| 10mM | 0.4127 mL | 2.0634 mL | 4.1267 mL | 8.2535 mL |
| 20mM | 0.2063 mL | 1.0317 mL | 2.0634 mL | 4.1267 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.