Felbamate (W-554; ADD-03055)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $450 | Check With Us |
| 500mg | $720 | Check With Us |
| 1g | $1080 | Check With Us |
: Cat #: V2505 CAS #: 25451-15-4 Purity ≥ 98%
Description: Felbamate (also known as ADD-03055), an antagonist at the NMDA-associated glycine binding site, is an anti-epileptic drug used in the treatment of epilepsy.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 238.24 |
|---|---|
| Molecular Formula | C11H14N2O4 |
| CAS No. | 25451-15-4 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 48 mg/mL (201.5 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 3 mg/mL (12.59 mM) | |
| SMILES Code | NC(OCC(C1=CC=CC=C1)COC(N)=O)=O |
| Synonyms | ADD-03055; W-554; W 554; W554; ADD03055; ADD 03055; Felbamate; brand name: Felbatol; Felbamyl; Taloxa. |
| Protocol | In Vitro | Felbamate (W-554) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.1974 mL | 20.9872 mL | 41.9745 mL | 83.9490 mL |
| 5mM | 0.8395 mL | 4.1974 mL | 8.3949 mL | 16.7898 mL |
| 10mM | 0.4197 mL | 2.0987 mL | 4.1974 mL | 8.3949 mL |
| 20mM | 0.2099 mL | 1.0494 mL | 2.0987 mL | 4.1974 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.