Clopidogrel sulfate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$250	Check With Us
5g	$450	Check With Us
10g	$675	Check With Us

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Cat #: V1301 CAS #: 120202-66-6 Purity ≥ 98%

Description: Clopidogrel sulfate (Plavix; Zyllt; Osvix; Plavitor, SR-25990C), the sulfate salt of Clopidogrel, is an orally bioavailable, thienopyridine class of antiplatelet agent acting as an irreversible inhibitor of ADP receptor (P2Y12).

References: Katsunobu Hagihara, et al. Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, Clopidogrel, and ticlopidine. Drug Metab Pharmacokinet. 2008;23(6):412-20.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	419.9
Molecular Formula	C16H16ClNO2S.H2SO4
CAS No.	120202-66-6
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 83 mg/mL (197.7 mM)rr
	Water: 78 mg/mL (185.7 mM)rr
	Ethanol: 46 mg/mL (109.5 mM)
SMILES Code	O=C(OC)[C@H](C1=CC=CC=C1Cl)N2CCC3=C(C=CS3)C2.O=S(O)(O)=O
Synonyms	SR-25990C; Plavix; (S)-Clopidogrel; Clopidogrelum; Zyllt. Clopidogrel sulfate; Osvix; Plavitor, SR 25990C; SR-25990C; SR25990C; SR 25990.

Protocol	In Vitro	Clopidogrel hydrogen sulfate (1.5 mM； 12 and 24 h) Upregulate TRIB3 and CHOP expression in a concentration and time-dependent manner, as measured by real-time PCR and western blotting analysis

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3815 mL	11.9076 mL	23.8152 mL	47.6304 mL
5mM	0.4763 mL	2.3815 mL	4.7630 mL	9.5261 mL
10mM	0.2382 mL	1.1908 mL	2.3815 mL	4.7630 mL
20mM	0.1191 mL	0.5954 mL	1.1908 mL	2.3815 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.