KN-92

This product is for research use only, not for human use. We do not sell to patients.

KN-92
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$690Check With Us
500mg$1150Check With Us
1g$1725Check With Us

Cat #: V2578 CAS #: 176708-42-2 Purity ≥ 98%

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Molecular Weight (MW)456.98
Molecular FormulaC24H25ClN2O3S
CAS No.176708-42-2
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 50 mg/mLrr
Water:<1 mg/mLrr
Ethanol: <1 mg/mL
SMILES CodeO=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2CN(C/C=C/C3=CC=C(Cl)C=C3)C)=O.[H]Cl
SynonymsKN-92 HCl; K92; K 92.
ProtocolIn VitroKN-93 (5-50 μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1883 mL10.9414 mL21.8828 mL43.7656 mL
5mM0.4377 mL2.1883 mL4.3766 mL8.7531 mL
10mM0.2188 mL1.0941 mL2.1883 mL4.3766 mL
20mM0.1094 mL0.5471 mL1.0941 mL2.1883 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.